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diagnosis management neurology syndrome genetics pediatrics 21hydroxylasedeficiency 21ohd als amyotrophic anesthesia anesthesiology barre bullous checklist cushings ddxof dermatology diabetes diabeticketoacidosis
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... diabetes Key signs ... /symptoms of HHS ... /DKA: Both: Polyuria
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Crises can be precipitated ... The underlying pathophysiology ... to ischaemia. 2) ... #Features #Signs ... #Symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
out of cells may cause ... +++ fluids. 2) ... Signs/Symptoms/Complications ... #pathophysiology ... #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Acne • Coarse features ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia Causes: thrombus, fat, amniotic fluid, air/gas. Signs: hypotension, tachycardia,
Guidelines for Crises ... Signs: hypotension ... decreased ETCO2 Symptoms ... then 90 mg over 2 ... Guidelines for crises
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... dermis Clinical Signs ... /Symptoms/Exam findings ... - Erosions and crusts ... topical steroids 2.
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... failure Clinical Features ... : • Many symptoms ... Diagnosis #Management #Signs ... #Symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Diagnosis and Clinical Features ... , oral cavity) Caused ... Hyperpigmentation is not a feature ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
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