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diagnosis management neurology syndrome 21hydroxylasedeficiency 21ohd barre bullous ddxof dermatology diabetes diabeticketoacidosis differential disease em encephalopathy endo features gbs genetics
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... diabetes Key signs ... /symptoms of HHS ... Pathophys #EM #IM
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
out of cells may cause ... +++ fluids. 2) ... Signs/Symptoms/Complications ... #pathophysiology ... #endocrinology
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Crises can be precipitated ... The underlying pathophysiology ... to ischaemia. 2) ... #Features #Signs ... #Symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
dermis Clinical Signs ... /Symptoms/Exam findings ... - Erosions and crusts ... topical steroids 2. ... feasible CMC IM
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... RIPE therapy for 2 ... intervention CMC IM
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
• Hypertensive crisis ... Etiology: • Pathophysiology ... Neurological symptoms ... the underlying cause ... until cause identified
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Incidence: 1 to 2 ... cases per 100,000 ... than one after symptom ... the underlying pathophysiology ... Hospital of Baltimore IM
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... develops later 2. ... • Bilateral signs ... and/or symptoms ... • Infectious causes
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