11 results
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Hypercortisolism - Diagnosis ... and Clinical Features ... same precursor as ... #signs #symptoms ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Acne • Coarse features ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... worrisome EKG features ... #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... and with limb features ... fasciculations Common Symptoms ... more regions 3.
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... for metabolizing 3 ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Phosphatase: • Other causes
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... failure Clinical Features ... are not caused ... mediators such as ... #Management #Signs
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... Signs of immunodeficiency ... may appear 3-9 ... /Symptoms/Findings ... Agammaglobulinemia #XLinked #pathophysiology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Alterations: - Sensory features ... • Bilateral signs ... and/or symptoms ... • Infectious causes
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... • The cardinal features ... is found in 1/3 ... than one after symptom ... the underlying pathophysiology
Subacute Thyroiditis

Also known as: de Quervain’s thyroiditis, granulomatous thyroiditis, or viral thyroiditis

What?
Postviral inflammatory process caused by
Thyroiditis Also ... inflammatory process caused ... ↓ TSH levels (3) ... #deQuervains #endocrinology ... #thyroid #diagnosis