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diagnosis differential management hematology vasculitis workup bronchiectasis chronic classification cll fungal hemophagocytic hlh infections infectiousdiseases leukemia lymphocytic lymphohistiocytosis mycoses neuritis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... internal organs 3 ... and Symptoms: ... ), PAH (pulmonary ... Scleroderma #SSc #rheumatology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
caucasian • Symptoms ... visual loss (avg. 3/ ... Unilateral • Signs ... other auto-immune diseases ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
affects infants < 3 ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
or proteinase 3 ... Presentation - Systemic Symptoms ... purpura: strong sign ... are proteinase 3 ... differential #diagnosis #rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Digital clubbing (2-3% ... Nasal polyps and signs ... , in advanced disease ... mycobacteria Treatment
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3 ... Differential #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... Agranulocytosis 3. ... microglobulin Treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... 3) Abdominal, ... extrapulmonary disease ... or meningitic disease ... 40% Invasive Disease
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