12 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
TB: • HIV • Recent ... Progression: (+) Immune ... rest LTBI (-) Immune ... • HIV: 2/3 pulmonary ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
TB: • HIV • Recent ... Progression: (+) Immune ... rest LTBI (-) Immune ... • HIV: 2/3 pulmonary ... TB #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
or proteinase 3 ... Necrotizing, pauci-immune ... Presentation - Systemic Symptoms ... purpura: strong sign ... are proteinase 3
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
caucasian • Symptoms ... Unilateral • Signs ... TREATMENT • IV ... or other auto-immune ... diseases By
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... HTN • Check: HBV ... • Progressive symptoms ... or proteinase 3
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... increased B-cell activity ... → local immune ... Pulmonary: dyspnea ... #Signs #Symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... improves CD4 count in 3- ... pericarditis, peritoneal disease ... • Persistently active ... Differential #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
underlying genetic immune ... affects infants < 3 ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... cells are the immune ... fasciculations Common Symptoms ... more regions 3. ... neurology #diagnosis #management
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Pneumonia: • 3 ... • CT: Halo sign ... Constitutional symptoms ... #AIDS #pulmonary ... differential #diagnosis #infectiousdiseases