11 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
intracellular rod-shaped bacteria ... Progression: (+) Immune ... rest LTBI (-) Immune ... • HIV: 2/3 pulmonary ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
intracellular rod-shaped bacteria ... Progression: (+) Immune ... rest LTBI (-) Immune ... • HIV: 2/3 pulmonary ... TB #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
or proteinase 3 ... Necrotizing, pauci-immune ... Presentation - Systemic Symptoms ... purpura: strong sign ... are proteinase 3
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3 ... Thrombosis and arterial
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
caucasian • Symptoms ... Unilateral • Signs ... TREATMENT • IV ... or other auto-immune ... diseases By
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Digital clubbing (2-3% ... Nasal polyps and signs ... cultures (sputum for bacteria ... , CCP, ANCA • HIV
Spontaneous Bacterial Peritonitis
DIAGNOSTICS
Paracentesis: 
 • Calculate absolute PMN count (total WBC x PMN %)
 • Correct
Treat if other signs ... • First-line: IV ... only if worsening symptoms ... advanced liver disease ... SBP #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... improves CD4 count in 3- ... drug-resistant infection, bacterial ... pericarditis, peritoneal disease ... Differential #Diagnosis #Management
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Pneumonia: • 3 ... • CT: Halo sign ... Constitutional symptoms ... #AIDS #pulmonary ... differential #diagnosis #infectiousdiseases
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
cells are the immune ... Presentation: - Disease ... fasciculations Common Symptoms ... more regions 3. ... neurology #diagnosis #management