10 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Hematuria, Hemoptysis, Peripheral ... ANCA-positive vasculitis ... polyangiitis, Microscopic ... ANCA-negative vasculitis ... differential #diagnosis #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... urine sediment Microscopic ... Diagnostic of GN or vasculitis ... causes #urology #nephrology ... #renal #urine #blood
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... glomeruli, and peripheral ... Large Vessel: Blood ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Glomerulonephritis - Peripheral ... Hyperviscosity Syndrome ... skin necrosis, peripheral ... - GPA, EGPA, microscopic ... classification #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Investigations: full blood ... dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... screen, including blood ... Differential #Diagnosis #nephrology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... (inflamed blood ... rash #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... polyangiitis), MPA (microscopic ... sparing of the lung periphery ... reveals increasing blood ... FINDINGS: • U/A: microscopic
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulses, bruits, or blood ... (PR3-ANCA)): Microscopic ... • Behcet syndrome ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
recurrentis on Peripheral ... Blood Smear 23M ... resolved after 2-3d ... Syndrome: 3d of ... recurrentis #BloodSmear #microscopy