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diagnosis ana antibodies classification cryoglobulinemia cryoglobulins dermatologic dermatology differential disease gpa granulomatosis laboratory management patterns polyangiitis rash rheumatic rheumatoid sjogrens
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Using fluorescence microscopy ... likely it will be clinically ... , Sjögren Syndrome ... ANA #patterns #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... arthralgia, and arthritis ... vasculitis - GPA, EGPA, microscopic ... SLE), rheumatoid arthritis ... classification #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... erythematosus (SLE) - Antinuclear ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... • Giant cell arteritis ... rash #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... salivary ducts Clinical ... Cryoglobulinemia (4%-12%), Raynaud ... Arthralgia and Arthritis ... #Rheumatology #
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