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nephrology differential causes high hyperkalemia management microscopy blood casts gitelman glomerular hematuria hypokalemia hypomagnesemia low magnesium pathology pathophysiology pulmonary rhabdomyolysis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... - Alport syndrome ... of glomerular disease ... #nephrology #renal
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... Differential Diagnosis ... polyangiitis, Microscopic ... #diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Haemolytic-uraemic syndrome ... Nephrotic syndrome ... #nephrology #pathology ... #comparison #table ... #diagnosis #microscopy
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and Disease ... tubulointerstitial nephritis, renal ... Fatty - Nephrotic syndrome ... #Differential #Microscopy ... #Diagnosis #Nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... - Tumor lysis syndrome ... • Addison’s disease ... #causes #potassium ... #high #nephrology
Causes of Hypomagnesemia • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
steatorrhea) • Renal ... osmotic diuresis, Potassium ... disease • Drugs ... #differential #diagnosis ... #nephrology #magnesium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... • Recent IV potassium ... - Tumor lysis syndrome ... • Addison’s disease ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... of underlying disease ... Monitor potassium ... #Differential #Diagnosis ... causes #treatment #nephrology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... affects the skin, neurologic ... cognitive impairment, neurologic ... (PR3-ANCA)): Microscopic
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
• Hypokalemia (renal ... potassium wasting ... • Autoimmune disease ... , Renal tubular ... #diagnosis #nephrology
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