18 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... propylthiouracil) - β-lactam
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Differential ... Framework and Clinical ... Manifestations Causes ... HF • Moderate pulmonary ... beriberi #nutrition #pathophysiology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... Causes of Lactate ... output - Acute pulmonary ... - Compartment syndrome ... 30mmHg) - Severe anemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Legionnaires disease • Pulmonary ... • Tumor lysis syndrome ... disease #LDH #Lactate
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... - Drugs (Beta lactam ... G6PD deficiency) ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Out Secondary Causes ... or folic acid deficiency ... treatments • Copper deficiency ... blood count with differential
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... • Severe iron deficiency ... anemia (reduced ... Acute Coronary Syndrome ... Infarction • Pulmonary
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... ) D D-lactate ... (short bowel syndrome ... Renal failure (uremia ... Classically” noted with pulmonary
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Edema - Differential ... Framework NCPE Pathophysiology ... Causes include: ... ischemic changes CXR ... respiratory distress syndrome
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical ... Hypo-Mg2+ • Vitamin deficiency ... • Vitamin D deficiency ... #Nutrition #Differential ... #Diagnosis #Pathophysiology