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diagnosis hematology management oncology rheumatology atlas beaus classification clinical common cvid differential diseases erythematosus fingernails fungal gca giantcell hodgkins hypogammaglobulinemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... Physical Exam/Signs ... • Neutropenia, anemia ... #Chronic #Lymphocytic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... factor (GCSF) treatments ... low and appear abnormal ... marrow studies Treatment ... Immunosuppressive treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... systemic sx + signs ... systemic complaints- anemia ... Treatment of GCA ... GCA #Temporal #Signs
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Lymphoma or other cancers ... gastric and breast cancer ... Granulomatous lymphocytic ... autoimmune hemolytic anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... products that define normal ... Hodgkin Lymphoma Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lymphopenia, low PLT • Anemia ... (C3 and C4) • ds-DNA ... with Lupus: • Chronic ... leukemia • Lung cancer ... • Cervical cancer
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... CRP GCA (Giant Cell ... fluid (CSF) is abnormal ... elevated protein, lymphocytic ... Eosinophilia, asthma, chronic
Nail Pathologies - Findings in or Near Nails Paronychia A superficial infection of the proximal and lateral
Chronic infections ... disease and lung cancer ... include diabetes, anemia ... Nail #Diseases #Abnormal ... Diagnosis #Clinical #Signs
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
85% • < 50% in chronic ... count (mainly lymphocytes ... level • A low or normal ... becomes a yeast cell ... Meningitis, septic arthritis
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