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hematology workup arthritis causes joint management pain agglutinin algorithm anemia approach autoimmune blood classification cold comparison degenerative disease disorders effusions
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Mycoplasma, EBV, HIV ... younger pts) Differential ... test #cold # ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
diagnostic hallmark ... low, tests to detect ... indirect antiglobulin tests ... WBC count and differential ... #Workup #Hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential ... Diagnosis Framework ... sensation distal to the ... Brucellosis - Viruses: HIV ... #diagnosis #msk
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... K), H. pylori test ... thyroid function test ... #Workup #hematology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
e.g., congenital hip ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential ... #diagnosis #arthritis
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain with rest ... motion (relieved by rest ... knee hip and L/ ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
Hearing Loss - Differential ... Diagnosis Framework ... Noise trauma ○ MS ... zoster virus ○ HIV ... #Diagnosis #otology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... Diagnosis Framework ... spine, shoulders, hips ... #Diagnosis #MSK ... #rheumatology #
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
indirect Coombs test ... inflammatory cytokines in the ... Extremely rare - HIV ... #Transfusions #diagnosis ... #management #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... We may ask why are ... Ask some questions ... Best to have an ... #Polycythemia #Differential
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