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hematology workup agglutinin anemia approach arthritis causes classification cold comparison degenerative disease disorders inflammatory joint jointdisease jointpain management pain pathophysiology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Mycoplasma, EBV, HIV ... younger pts) Differential ... sensitize red blood ... test #cold #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
low, tests to detect ... of Peripheral blood ... indirect antiglobulin tests ... WBC count and differential ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... plateletcount), peripheral blood ... K), H. pylori test ... #Workup #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
indirect Coombs test ... inflammatory cytokines in the ... Extremely rare - HIV ... #Transfusions #diagnosis ... #management #hematology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain with rest ... after > 1 hr • Blood ... knee hip and L/ ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
e.g., congenital hip ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential ... #diagnosis #arthritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis Framework ... pulses, bruis, or blood ... Large Vessel: Blood ... retinopathy Lab Tests ... #diagnosis #rheumatology
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