23 results
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
disease Inflammatory ... Joint Disease ... knee hip and L/ ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... e.g., congenital hip ... #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Diagnosis Framework ... Fever/Chills/Joint ... sensation distal to the ... #diagnosis #msk
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... Mycoplasma, EBV, HIV ... younger pts) Differential ... test #cold # ... #hematology #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip ... dz difficult to see ... diagnosis #causes ... #hematology
Bone Deformity / Limp - Differential Diagnosis Algorithm 
Infection
 • Septic Arthritis
 • Cortical Hypertrophy
 •
Diagnosis Algorithm ... JointHip Dysplasia ... Knee Joint • ... Deformity #Limp #MSK ... #Differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... Diagnosis Framework ... spine, shoulders, hips ... #Diagnosis #MSK ... #rheumatology #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for the disease ... low, tests to detect ... indirect antiglobulin tests ... WBC count and differential ... #Workup #Hematology
Iliotibial Band Friction Syndrome - MSK Radiology
Imaging Findings:
 • The iliotibial band (ITB) is thickened with
Friction Syndrome - MSK ... Findings of chronic disease ... Differential diagnosis ... Syndrome #Radiology #diagnosis ... #msk #clinical