9 results
Heparin-Induced Thrombocytopenia (HIT) Evaluation Algorithm

- Dr. Josh Farkas @PulmCrit

#4TScore #HITT #Algorithm #HeparinInduced #Thrombocytopenia #Diagnosis #Criteria #Hematology
Heparin-Induced Thrombocytopenia ... HIT) Evaluation Algorithm ... #4TScore #HITT #Algorithm ... #Diagnosis #Criteria ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Heart Valve) #Thrombocytopenia ... #Causes #Hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLE Diagnostic Criteria ... NEUROLOGIC - HEMOLYTIC ANEMIA ... (<1000/MM3) - THROMBOCYTOPENIA ... absence of hemolytic anemia ... #Diagnosis #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
: ↑↑ ferritin, Anemia ... , Thrombocytopenia ... the following 8 criteria ... Lymphohistiocytosis #diagnosis #hematology ... #criteria
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... ARUPLabs #Hemolytic #Anemia ... #workup #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... , thrombocytopenia ... (MDS) Most met criteria ... Autoinflammatory #Somatic #rheumatology
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
have no clinical criteria ... Albumin ≤3.0 g/dL, anemia ... purposes of this algorithm ... under nail bed of fingers ... Disease #Incomplete #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... with leukopenia, anemia ... , and thrombocytopenia ... Histopathologic criteria ... #Rheumatology