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diagnosis differential rheumatology management pulmonary autoimmune behcet bronchiectasis classification erythematosus lupus myopathy myositis renal signs sle syndromes systemic treatment vasculitides
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
to local skin injury ... meningitis), MCC CNS symptoms ... Recurrent and chronic ... Glucocorticoids 5-ASA ... management #signs #symptoms
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes (PRS) ... life-threatening diseases ... injury), Coags ... anti-GBM) Other tests ... or serologies + symptoms
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
bronchial wall injury ... inflammation Symptoms ... Connective tissue diseases ... • Mounier-Kuhn syndrome ... Laboratory: • ANA
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... retinopathy Lab Tests ... LFT • ESR • ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Shrinking lung syndrome ... • May involve PNS ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms ... with Lupus: • Chronic
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... Dermatomyositis Symptoms ... aspiration > 50% of pts ... ANTI-MITOCHONDRIAL MYOPATHY: • Chronic ... muscular atrophy • Chronic
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