5 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... , anti-GBM ab, ANA ... #differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... progressing GN • New pulmonary ... : • Behçet Syndrome ... • Cogan Syndrome ... LFT • ESR • ANA
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Autoimmune ANCA vasculitis ... Renal Syndromes ... palpable purpura 2/2 vasculitis ... #Renal #Syndromes
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... polymorphisms alter ... galactose-deficient IgA1 (GD-IgA1 ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Scleromalacia perforans • Pulmonary ... Vascular: Rheumatoid vasculitis ... Tubulo-interstitial nephritis, AA ... Thrombocytosis, Felty's syndrome ... Signs #Symptoms #diagnosis