15 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Intestine - Other causes ... - Drugs - Primary ... #Algorithm #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
, Alkaline Phosphatase ... : primarily within ... liver Alkaline ... clearance - AP ... Pathophysiology #Diagnosis
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Urobilinogen • + urinary ... #Workup #Hematology ... #Diagnosis *
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... unclear, or if a primary ... #Causes #Workup ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... Phosphatase: • Other causes ... • Elevation of urinary ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... PBC Labs: • Alkaline ... obstruction • ALP ... or higher • Liver ... #workup #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... /Quantity: • Primary ... deficiency • Liver ... vasculitis - GPA ... #hematology #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
RPGN has three primary ... pathophysiologic causes ... ANCA (C-ANCA): GPA ... #differential #diagnosis ... #algorithm #rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... and hematologic ... ALT, alanine aminotransferase ... #diagnosis #management
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... an underlying cause ... Better call hematology ... #Algorithm #workup ... #hematology