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Acid-Base Disorders - Differential Diagnosis Framework

• Respiratory Acidosis
• Respiratory Alkalosis
• Metabolic Acidosis
•

Acid-Base Disorders ... - Differential ... Diagnosis Framework ... #Disorders #nephrology ... diagnosis #acidosis

Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)

Anion Gap (AG). 2) ... 3) Now, look at ... Differential Diagnosis ... Disorders #Evaluation #workup ... Diagnosis #acidosis

Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the

Acid Base and Blood ... 2. pCO2 - What’s ... nickmmark #acidbase #workup ... #algorithm #diagnosis ... #acidosis #alkalosis

Hypokalemia Differential Algorithm
Acidosis
- RTA
- Diarrhea
pH Normal
1. Decreased Mg
2. Intracellular Shift

Hypokalemia Differential ... Algorithm Acidosis ... #Algorithm #Diagnosis ... #Causes #Workup ... #Nephrology

Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
• Cl- responsive metabolic alkalosis

- Differential ... Diagnosis Algorithm ... - Normal/low ... • Normal acid-base ... #Differential #

Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation:
1. Acidemia or Alkalemia?
2.

Acid Base Disorders ... 2. ... Diagnosis: Causes ... #Summary #Nephrology ... bloodgas #Acid #Base

Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
• Low Urine Cl-: Vomiting, NGT

Primary Metabolic Alkalosis ... - Differential ... Diagnosis Algorithm ... Volume Depleted 2° ... #nephrology

Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
• Kidney loss of Cl-

• Normal/low ... poisoning Normal acid-base ... urine #Algorithm #nephrology ... #differential # ... diagnosis

Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
• Low Urine Cl-: Vomiting,

Primary Metabolic Alkalosis ... - Differential ... Diagnosis Algorithm ... Volume Depleted - 2° ... #Nephrology #Causes

Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all

Acid Base Disorders ... Step 2: Look at ... Step 7: Make the diagnoses ... using the differentials ... #differential

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