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diagnosis causes algorithm medications metabolic kidney alkalosis hyperkalemia potassium stones high management nephrolithiasis table abg acid acidbase acidosis acutekidneyinjury aki
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #medications #druginduced
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Injury • Pre-Renal ... @kdjhaveri #DrugInduced ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Epithelial Cells Renal ... syndrome - Na-K-2Cl ... receptor Distal renal ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... • High Urine Cl ... hyperaldosteronism • High PRA: Renal ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... • High Urine Cl ... hyperaldosteronism • High PRA: Renal ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
- Urine Na/K/Cl ... protein/Cr - Renal ... - 45% - Pre-renal ... AcuteKidneyInjury #AKI #Nephrology ... Algorithm #Causes #Differential
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
importance in renal ... production of renal ... hormones that act ... NSAIDs #Kidney #renal ... #nephrology #pharmacology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • NSAIDs • ACE ... deficiency • Renal ... #hyperkalemia #differential ... potassium #high #nephrology
Causes of Polyuria - Differential Diagnosis Algorithm Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min) Osmotic
of Polyuria - Differential ... Recovery from Acute Renal ... GI Bleed) • NaCl ... #Polyuria #Nephrology ... #Differential #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • NSAIDs • ACE ... deficiency • Renal ... #hyperkalemia #differential ... potassium #high #nephrology
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