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management hematology differential oncology algorithm causes lupus disease erythematosus neurology sle systemic table clinical workup ana antinuclear autoantibodies classification criticalcare
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... antibodies) • ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... #diagnosis #associations
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... (aPL): • Lupus ... (aCL) • Anti-ß2 ... to be present Treatment ... Antiphospholipid #Syndrome
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific Antibodies ... Anti-Synthetase Syndrome ... Myositis #Specific #Antibodies ... MSAs #clinical #diagnosis ... #rheumatology #
Migraine - Preventative Treatments • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
- Preventative Treatments ... Beta-blockers, ACE ... peptide monoclonal antibodies ... #Preventative #Treatment ... prophylaxis #prevention #pharmacology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Hypereosinophilic Syndrome ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... scleroderma) - Anti-Scl ... cases • Sjögren syndrome ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
myasthenia Diagnosis ... Labs: - AchR antibodies ... assay - MuSK antibodies ... - LRP4 antibodies ... Myasthenia #Gravis #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... only curative treatment ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
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