12 results
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
at anytime if toxicity ... Theophylline - For i/v infusion ... - Continuous infusion ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
Local Anaesthetic Toxicity ... Signs of severe toxicity ... tachyarrhythmias may all ... anaesthetic (remember infusion ... Diagnosis #Management #Workup
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Consider IL NS/LR infusion ... Setup - Ultrasound ... and Survey 4) Workup ... Management #Summary #criticalcare ... #treatment #workup
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion ... Propofol #Related #Infusion ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
its Chloride (Cl ... ECF and ICF both work ... blood flow and perfusion ... #foamed #criticalcare ... diagnosis #treatment #pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... importantly, bedside ultrasound ... Adequate perfusion ... heartfailure #chf #criticalcare ... icu #clinical #pharmacology
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
reservoir bag and APL ... rate, rhythm, perfusion ... local anaesthetic toxicity ... Diagnosis #Management #Workup
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic ... Delirium #PAD #ICU #CriticalCare
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
reservoir bag and APL ... rate, rhythm, perfusion ... local anaesthetic toxicity ... Diagnosis #Management #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... rate, rhythm, perfusion ... Local anaesthetic toxicity ... Diagnosis #Management #Workup