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differential hematology management acidosis aclf acute aplastic causes cirrhosis classification dehydrogenase dili druginduced elevated elevation failure gastroenterology laboratory lactic ldh
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Injury (DILI) ... #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... non-essential drug/HDS treatments ... #Injury #Diagnosis ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... #diagnosis #algorithm ... #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... - Differential Diagnosis ... RBCs, muscle, liver ... Legionnaires disease • Pulmonary ... disease #LDH #Lactate
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... : - Hepatitis ... Treatment: ... #oncology #hematology ... #diagnosis #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... or renal injury ... output - Acute pulmonary ... 30mmHg) - Severe anemia ... Injury: • Reduced
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
common - GI tract, liver ... • No CRAB - no anemia ... lytic lesions • Lactate ... Bone marrow Treatment ... #Plasmacytoma #Oncology
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