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algorithm oncology classification extravascular hemolysis lymphoma management mds myelodysplasia myelodysplastic nonpalpable palpable petechial physicalexam purpura rash rheumatology syndromes testing thrombocytopenia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... lymphoproliferative disorders ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... #Disorders #Differential ... #Diagnosis #Causes ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... with or without platelet ... Agglutination - Cold ... #Anemia #Differential ... #workup #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... deficiency Work ... #Causes #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
reflection of intravascular ... hemolysis Platelet ... anemia Indirect ... WBC count and differential ... #Workup #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... Lymphoma Workup ... - Low Hb and platelets ... classification #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... by bleeding (petechiae ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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