7 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... -74%] • Blood tests ... severity of the disease ... #rheumatology # ... dermatology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... Diagnosis #Management #Hematology ... #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management #Dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Orange or Hep C Clinical ... cells can indicate disease ... • Richter’s Syndrome ... workup #oncology #hematology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... had more severe disease ... Papillary carcinoma • Clear ... diagnosis #management #rheumatology ... #dermatology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... von Willebrand disease ... Marfan syndrome, ... History #peds #pediatrics ... #diagnosis #hematology