31 results
Eosinophilic Pneumonia
When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
common diagnoses Acute ... Effusions - Rare Peripheral ... tobacco hx, >60% asthma ... Consolidations AKA "inverse pulmonary ... Pneumonia #diagnosis #pulmonary
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
asthma • Mepolizumab ... q4 weeks • Peripheral ... q4 weeks • Peripheral ... #asthma #Biologic ... #pharmacology #pulmonary
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
therapies for Asthma ... , and ACO initially ... analysis with eosinophil ... ACO = asthma-COPD ... agonist; LAMA = long-acting
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases ... • Acute Eosinophilic ... 45yo, F; Hx of asthma ... Weeks) - Hx of asthma ... #pulmonary #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... FOR TESTING: • Peripheral ... for secondary causes ... (common causes ... are asthma, allergy
Causes of Cough and Hemoptysis
Acute Inflammation 
 - Laryngitis 
 - Tracheobronchitis 
 - Mycoplasma and
Causes of Cough ... and Hemoptysis Acute ... Tuberculosis - Lung ... Abscess - Asthma ... Cancer of the Lung
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Dermatitis - Asthma ... Mastocytosis - Acute ... Eosinophilic Leukemia ... Differential #Diagnosis #Causes
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
destructive sinusitis, pulmonary ... - Interstitial lung ... disease • Eosinophilic ... polyangiitis - Asthma ... . eosinophilia.
Causes of Hypoxemia- Differential Diagnosis Algorithm
Ventilation/perfusion Mismatch
 • Airway Disease (Asthma, COPD)
 • Vascular (PE*)
 •
Causes of Hypoxemia ... Airway Disease (Asthma ... • Interstitial lung ... Hypothyroidism Peripheral ... Diagnosis #Algorithm #Causes
Pediatric Dyspnea - Differential Diagnosis Algorithm
Stridor:
 • Croup
 • Foreign Body
 • Tracheitis
 • Epiglottitis
 •
Laryngospasm Wheeze: • Asthma ... Pneumonia • Asthma ... Ketoacidosis • Pulmonary ... Diagnosis #Algorithm #Causes ... #Peds #Pediatrics