10 results
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
cough, SOB • Chronic ... 45yo, F; Hx of asthma ... SOB, sinusitis, wheezing ... Weeks) - Hx of asthma ... , CF; Chronic cough
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
asthma • Mepolizumab ... q4 weeks • Peripheral ... q4 weeks • Peripheral ... #asthma #Biologic ... pharmacology #pulmonary #management
Eosinophilic Pneumonia
When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
Effusions - Rare Peripheral ... mechanical ventilation Chronic ... tobacco hx, >60% asthma ... Constitutional Symptoms - Peripheral ... edema" - Common Peripheral
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
therapies for Asthma ... , and ACO initially ... analysis with eosinophil ... ACO = asthma-COPD ... #Diagnosis #Management
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
with underlying asthma ... • Wheezing • Increased ... Aspergillus • Peripheral ... eosinophilia and ... pulmonary #diagnosis #management
Allergic Rhinitis
Mild to severe persistent nasal mucosal inflammation to specific allergic triggers
WHO? 
 • 1 in
Intermittent/Seasonal • Chronic ... Associations: • Asthma ... Clinical Features • Sneezing ... Rhinitis #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), EGPA (eosinophilic ... hemorrhage (DAH), asthma ... pulmonary nodules, asthma ... sparing of the lung periphery ... differential #diagnosis #management
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
hoarseness, and wheezing ... throat clearing, chronic ... Laryngitis • Asthma ... Disease #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• EGPA: - Eosinophilia ... , asthma, chronic ... glomeruli, and peripheral
Diagnosis of Multiple Chemical Sensitivity
In research, MCS is defined based on the following:20
1. It is chronic
It is chronic - ... Difficulty breathing/asthma ... irritability; sneezing ... #Differential #Management