15 results
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
, Asthma-COPD Overlap ... , asthma, and ACO ... analysis with eosinophil ... ACO = asthma-COPD ... Diagnosis #Management #ACOPD
Eosinophilic Pneumonia
When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
Eosinophilic Pneumonia ... Effusions - Rare Peripheral ... tobacco hx, >60% asthma ... Constitutional Symptoms - Peripheral ... edema" - Common Peripheral
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
asthma • Mepolizumab ... q4 weeks • Peripheral ... q4 weeks • Peripheral ... q8 weeks • Peripheral ... #asthma #Biologic
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Approach to Eosinophilic ... 45yo, F; Hx of asthma ... SOB, sinusitis, wheezing ... Weeks) - Hx of asthma ... food hx; Fever, wheezing
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... FOR TESTING: • Peripheral ... blood eosinophilia ... specific symptoms • Eosinophilia ... common causes are asthma
The infant with tachypnea or wheeze - Clinical Conditions to Consider
 - Bronchiolitis 
 - Pneumonia
Transient early wheezing ... - Non-atopic wheezing ... infection - Atopic asthma ... — recurrent wheezing ... #Diagnosis #Peds
Causes of Pediatric Wheezing - Differential Diagnosis Algorithm
CXR Abnormal:
 • Pulmonary Sequestration
 • Congenital Adenoid Cystic
Causes of Pediatric Wheezing ... Beta-Agonist: • Asthma ... Structural Anomaly #Wheezing ... Algorithm #Causes #Peds
Wheezing - Differential Diagnosis Framework - Not all that wheezes is asthma
Vibrations of turbulent flow against
Wheezing - Differential ... that wheezes is asthma ... Primary bronchi: - Asthma ... /COPD, Viral infections ... Kumfer @AnnKumfer #Wheezing
Cough - Diagnostic Schema

Infectious: URTI, LRTI, Bacterial, Viral
Irritant/Exposure: Allergic, Post-infectious, Pneumonitis, ACEi, PTX, Foreign Body
Airway Disease:
Airway Disease: Asthma ... , COPD, Sinusitis ... mycobacterial), Eosinophilic
An Algorithm for the Diagnosis of Wheezing and Stridor

Stridor: Louder, constant-pitch sound over central airways
Wheezing: Musical
the Diagnosis of Wheezing ... central airways Wheezing ... Lower Airway Wheezing ... Bronchoconstriction: Asthma ... , COPD, Anaphylaxis