7 results
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
Biologic therapy ... for eosinophilic asthma ... #eosinophilic #asthma ... #Biologic #therapy ... pharmacology #pulmonary #management
Causes of Pediatric Wheezing - Differential Diagnosis Algorithm
CXR Abnormal:
 • Pulmonary Sequestration
 • Congenital Adenoid Cystic
Causes of Pediatric Wheezing ... Beta-Agonist: • Asthma ... Endobronchial Disease ... Structural Anomaly #Wheezing ... Algorithm #Causes #Peds
Asthma GINA Guidelines 2019 
If Asthma is uncontrolled, first assess for adherence and inhaler technique -Then,
Asthma GINA Guidelines ... increase stepwise therapy ... tiotropium or biologics ... Stepwise #Guidelines #Management ... #StepUp #Therapy
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
with underlying asthma ... • Wheezing • Increased ... Aspergillus • Peripheral ... /- anti-fungal therapy ... pulmonary #diagnosis #management
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
Gastroesophageal Reflux Disease ... hoarseness, and wheezing ... Laryngitis • Asthma ... Failure of optimal therapy ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... hemorrhage (DAH), asthma ... pulmonary nodules, asthma ... sparing of the lung periphery ... differential #diagnosis #management
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... Anti-Smooth Muscle Abs (ASMA ... Hepatitis (eg Viral) Management ... treatment, though therapy ... AIH #Diagnosis #Management