463 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... Tuberculosis: can cause ... AM cortisol and ACTH ... AI present - ACTH
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Weakness, fatigue, nausea ... Adrenocorticotropic hormone (ACTH ... Baseline plasma ACTH ... High baseline ACTH ... normal baseline ACTH
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Diagnosis Algorithm ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Diagnosis #Algorithm #Causes
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
set of symptoms) caused ... antipsychotics, oxybutynin, ACh ... - Cholinergic: ACh ... Toxidromes #Comparison #Table
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: • ACTH ... test - Synthetic ACTH ... by endogenous ACTH ... Low • Plasma ACTH ... aldosterone - Low in cases
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Axis Response to ACTH ... unclear (often the case ... secondary AI Measure ACTH ... Diagnosis #Algorithm #ACTH
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
: Most Common Cause ... Adrenalitis Other causes ... is absent (low ACTH ... Causes of Secondary ... ACTH STIM TEST:
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
, oral cavity) Caused ... by excessive ACTH ... same precursor as ACTH ... polyuria in the case ... hypertension (90% of cases
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
Autoimmune:
 • Isolated
 • Polyglandular autoimmune syndrome 1
 •
Causes of Adrenal ... adrenomyeloneuropathy ACTH ... Diagnosis #Algorithm #Causes
Inpatient Cath Lab Indications
Cath Lab ASAP:
STEMI
NSTEMI:
1. Unstable/cardiogenic shock
2. Severe LV dysfunction or
3. Recurrent/persistent rest angina despite
Inpatient Cath Lab ... Indications Cath ... ventricular arrhythmia Cath ... high (5-7) risk Cath ... Rx: NSTEMI/UA: stable