296 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... Adrenocorticotropic hormone (ACTH ... Baseline plasma ACTH ... High baseline ACTH ... normal baseline ACTH
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Primary Adrenal Insufficiency ... primary adrenal insufficiency ... Secondary Adrenal Insufficiency ... secondary adrenal insufficiency ... secondary adrenal insufficiency
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Adrenal Insufficiency ... Primary Adrenal Insufficiency ... primary adrenal insufficiency ... apoplexy • Isolated ACTH-deficiency ... #Adrenal #Insufficiency
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal Insufficiency ... to a bolus of ACTH ... - Check ACTH ... - Low ACTH is ... ) #Adrenal #Insufficiency
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal Insufficiency ... Diagnosis Algorithm ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... SCVMCMed #Adrenal #Insufficiency
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Axis Response to ACTH ... secondary AI Measure ACTH ... AI #Adrenal #Insufficiency ... Diagnosis #Algorithm #ACTH
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Secondary Adrenal Insufficiency ... be low, while ACTH ... Low ACTH leads to ... Secondary #Adrenal #Insufficiency
Algorithm for the diagnosis of adrenal insufficiency (AI). The standard cosyntropin stimulation test (CST) may be
diagnosis of adrenal insufficiency ... ACTH, adrenocorticotropic ... Diagnosis #Endo #ACTH
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... skin (due to high ACTH ... PRIMARY adrenal insufficiency ... suggestive of adrenal insufficiency ... > 18, adrenal insufficiency
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal Insufficiency ... Causes of Adrenal Insufficiency ... Primary ovarian insufficiency ... AI present - ACTH ... Primary #adrenal #insufficiency