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diagnosis differential symptoms signs management cdc parasite infectiousdiseases cardiology endocrinology pharmacology algorithm psychiatry syndrome neurology treatment clinical nephrology complications adrenal
COVID-19 Life Cycle #COVID19 #LifeCycle #Timeline #Pathophysiology #Diagnosis
Cycle #COVID19 #LifeCycle ... #Timeline #Pathophysiology
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... Tuberculosis: can cause ... AM cortisol and ACTH ... AI present - ACTH
Fibrinolysis. Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
Plasmin then acts ... and urokinase act ... -antiplasmin), act ... Fibrinolysis #Pathway #Pathophysiology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Insufficiency - Pathophysiology ... be low, while ACTH ... Low ACTH leads to ... Insufficiency #Pathophysiology
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Weakness, fatigue, nausea ... Adrenocorticotropic hormone (ACTH ... Baseline plasma ACTH ... High baseline ACTH ... normal baseline ACTH
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal ... Diagnosis Algorithm ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Diagnosis #Algorithm #Causes
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Axis Response to ACTH ... unclear (often the case ... secondary AI Measure ACTH ... Diagnosis #Algorithm #ACTH
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: • ACTH ... test - Synthetic ACTH ... by endogenous ACTH ... Low • Plasma ACTH ... aldosterone - Low in cases
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... growth hormone, and ACTH ... LH, FSH, TSH, ACTH ... Headaches • Nausea ... mnemonic #GLFTAP #pathophysiology
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
: Most Common Cause ... Adrenalitis Other causes ... is absent (low ACTH ... Causes of Secondary ... ACTH STIM TEST:
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