790 results
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal ... specificity for AI ... > 15 excludes AI ... have diagnosed AI ... gland) #Adrenal
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Axis Response to ACTH ... indicates normal adrenal ... Measure ACTH: ... Diagnosis #Algorithm #ACTH
Algorithm for the diagnosis of adrenal insufficiency (AI). The standard cosyntropin stimulation test (CST) may be
the diagnosis of adrenal ... insufficiency (AI ... evaluation of adrenal ... secondary or tertiary AI ... Diagnosis #Endo #ACTH
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Pathophysiology Primary AI ... = adrenal glands ... be low, while ACTH ... Secondary AI = the ... Low ACTH leads to
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Diagnosis Algorithm ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Thrombophilia (adrenal ... Insufficiency #AI
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
AM cortisol and ACTH ... /dL -> Primary AI ... present - ACTH ... ug/dL Primary AI ... present - ACTH
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Adrenal Insufficiency ... Summary Primary Adrenal ... is absent (low ACTH ... ACTH STIM TEST: ... baseline cortisol and ACTH
Adrenal Crisis
Do not confuse acute adrenal crisis with Addison disease. In 1855, Thomas Addison described a
Adrenal Crisis ... confuse acute adrenal ... be a cause of adrenal ... hydrocortisonr #ACTH ... #AI ##adrenals
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm
Exogenous (ACTH-independent)
Endogenous
 • ACTH-dependent:
    - ACTH-secreting
Endogenous • ACTH-dependent ... : - ACTH-secreting ... Disease) - ACTH-secreting ... : - Adrenal ... hyperplasia - Adrenal
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... Adrenocorticotropic hormone (ACTH ... Baseline plasma ACTH ... High baseline ACTH ... normal baseline ACTH