56 results
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... - Evaluation of ... Axis Response to ACTH ... #Diagnosis #Algorithm
Algorithm for the diagnosis of adrenal insufficiency (AI). The standard cosyntropin stimulation test (CST) may be
Algorithm for the ... diagnosis of adrenal ... insufficiency (AI ... first-line test for evaluation ... of adrenal function
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal ... Insufficiency - Algorithm ... specificity for AI ... > 15 excludes AI ... Insufficiency #Algorithm
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Differential Diagnosis Algorithm ... ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Insufficiency #AI ... Differential #Diagnosis #Algorithm
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Pathophysiology Primary AI ... = adrenal glands ... be low, while ACTH ... Secondary AI = the ... Low ACTH leads to
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm
Exogenous (ACTH-independent)
Endogenous
 • ACTH-dependent:
    - ACTH-secreting
Differential Diagnosis Algorithm ... : - ACTH-secreting ... : - Adrenal ... hyperplasia - Adrenal ... Differential #Diagnosis #Algorithm
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
AM cortisol and ACTH ... /dL -> Primary AI ... present - ACTH ... ug/dL Primary AI ... present - ACTH
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Adrenal Insufficiency ... Summary Primary Adrenal ... is absent (low ACTH ... ACTH STIM TEST: ... baseline cortisol and ACTH
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Baseline plasma ACTH ... High baseline ACTH ... normal baseline ACTH ... Differential #Diagnosis #Algorithm
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Insufficiency: • ACTH ... test - Synthetic ACTH ... by endogenous ACTH ... Low • Plasma ACTH ... Insufficiency #Evaluation