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diagnosis management differential druginduced activation approach classification comparison dil disease erythematosus joint laboratory macrophage mas msk pain rheumatic rheumatoid syndrome
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... • Immunologic Workup ... • Immunologic Workup ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute ... C4) • ds-DNA: Kidney ... • Kidney biopsy ... Erythematosus #Diagnosis #Rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Chronicity: • Acute ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... Joint #Pain #MSK #rheumatology ... #approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... synovial fluid • Gout ... joint • Systemic lupus ... Screening Tests for Acute ... diagnosis #testing #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Heart, lung, and kidney ... erythematosus [SLE ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... #DIL #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... Vessels: Supply gut ... vasculitis, and SLE ... differential #diagnosis #rheumatology
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