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diagnosis management approach differential druginduced joint lupus pain comparison dil disease gout igg4 phenotypes related rheumatoid sle table
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
• Inflammatory arthritis ... : • Acute or chronic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... exam and imaging Treatment ... ideally limit for acute ... Leflunomide (LEF) • JAKi ... diagnosis #management #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Chronicity: • Acute ... • Acute = Viral ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
lesions, meninges, kidneys ... with response to treatment ... hypergammaglobulinemia, ↑ acute ... management #phenotypes #workup ... #treatment #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... • Immunologic Workup ... • Immunologic Workup ... comparison #table #rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
frequent attacks • Arthritis ... Dual-energy CT → MSU ... cortical bone Treatment ... gout treatment; ... #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... • Immunologic Workup ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment
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