11 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... 8.0 mg/dL • Potassium ... #TumorLysis #Syndrome ... #management #oncology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Anticonvulsants as ... Stevens-Johnson Syndrome ... , asthenia • Neurologic ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ≥ 8 mg/dL • Potassium ... MatthewHoMD #TLS ... Syndrome #diagnosis ... #management #oncology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Renin-secreting tumor ... acid, Liddle's Syndrome ... , Gitelman's syndrome ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... #Lysis #Syndrome ... #TLS #Pathophysiology ... #oncology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Clinicians should also ... , Gitelman's syndrome ... Renin-secreting tumor ... algorithm #causes #nephrology ... #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
complications such as ... treated with IV potassium ... Renin secreting tumor ... #differential #potassium ... #nephrology #low
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... Intracellular Urate, Potassium ... Leukemia #Hematology #Oncology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
evaluation should also ... include a: • Neurologic ... tympanic membrane • Neurologic ... II ○ Susac’s syndrome ... Cerebellopontine angle tumor
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... myoclonic movements, tremors ... #PhysicalExam #neurology