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diagnosis management clinical differential cardiology algorithm pharmacology treatment radiology causes pathophysiology pocus ekg signs table criticalcare ecg neurology symptoms comparison
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
5X ULN • AST/ALT ... AST declines > ALT ... • Hypocalcemia/Late ... • HAGMA • Late ... ringers - Initial rate
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT ... /ULN ALT) / (Alk ... to liver than ALT ... • ALT: Specific ... synthesis - rises later
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
to liver than ALT ... • ALT: Specific ... synthesis rises later ... • AST: ↑ • ALT ... - ALP > AST/ALT
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Pneumocystis pneumonia (late ... ischemic hepatitis (ALT-to-LDH ... viral hepatitis (ALT-to-LDH
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19 IL-6 activates T cells and macrophages, among other cell types (see
be repeated 12h later ... Transaminitis (AST, ALT
Fetal Heart Rate Decelerations Decelerations in fetal heart rate are more complicated and should be interpreted according
Fetal Heart Rate ... in fetal heart rate ... deceleration—variable, early, and late ... Decels #Early #Late
BRUE (Brief Resolved Unexplained Event) Algorithm ALTE (Apparent Life Threatening Event) is out, replaced with a new
Event) Algorithm ALTE ... UnexplainedEvent #Algorithm #ALTE
Stages of Syphilis Early Primary: • Painless chancre • Regional lymphadenopathy Early Secondary: • Fever, malaise • Rash
Pharyngitis • Condyloma lata ... year of infection Late ... Late Latent: •
LYME DISEASE TREATMENT: PROPHYLAXIS, EARLY LYME, EARLY DISSEMINATED LYME, LATE LYME, CHRONIC LYME #Management #Treatment #LymeDisease #Antibiotics
DISSEMINATED LYME, LATE ... Antibiotics #Early #Late
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
• Jaundice (later ... Nucleotidase • ALT
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