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algorithm differential amiodarone common cvid gravis hypogammaglobulinemia immunodeficiency induced leukemia lung myasthenia naildisorders neurology oncology pulmonary rheumatology sapho secondary systemic
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Arthritis • SLE ... Fatigue Syndrome ... #Chronic #Fatigue
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... - Generalized fatigue ... first step in immunologic ... inhibition - Chronic ... #management #neurology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... DDX - Other causes ... hypogammaglobulinemia #immunology ... #hematology #diagnosis ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... CML Symptoms: • Fatigue ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... Rule out other causes ... antiinflammatory properties e.g ... diagnosis #management ... #Dermatology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
hypersensitivity/immunologic ... respiratory distress syndrome ... (e.g., chronic ... Fatigue and/or weight ... Exclude other causes
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