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differential rheumatology algorithm causes systemic activation allergy amiodarone common cvid erythematosus essential et fatigue gravis hemophilia hypogammaglobulinemia immunodeficiency induced leukemia
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Arthritis • SLE ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g ... Fatigue Syndrome
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Chronic ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
may take 6 to 8 ... Autoimmunity • Chronic ... hypogammaglobulinemia #immunology ... #hematology #diagnosis ... #management
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... mixing study (aPTT may ... hemophilia type (e.g ... Chronic Management ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... : - Neuro: AMS ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(MAS) Classified ... manifestation of MAS ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... • A clinical diagnosis ... antiinflammatory properties e.g ... diagnosis #management ... #Dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... . hematologic) ... vein thrombosis Hematologic ... with Lupus: • Chronic ... Erythematosus #Diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Serologic and EMG ... first step in immunologic ... inhibition - Chronic ... #management #neurology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
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