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diagnosis hematology anemia cardiology agglutinin algorithm cold dehydrogenase elevated infections infectiousdiseases intermittent laboratory lactate ldh management nonpalpable palpable patterns periodic
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Acute bacterial endocarditis ... • Infective endocarditis ... with profound hemolysis ... #Patterns #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... mechanical cardiac valve ... bartonella (oroya fever ... #Anemia #Differential ... Algorithm #workup #hematology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... night sweats, fever ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... Persistent bacteremia/fevers
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... CTD (SLE) - Viral ... mountain spotted fever ... • Bacterial endocarditis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... - Prosthetic valves ... ratio < 1.5) from viral ... myocarditis, rheumatic fever ... Dehydrogenase #Elevated #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
CAS): - Due to Viral ... - Polyclonal - Viral ... younger pts) Differential ... Symptoms: High fevers ... #hematology #diagnosis
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential ... involves aortic and mitral ... night sweats, fever ... Persistent bacteremia/fevers ... #Endocarditis #Differential
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