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diagnosis rheumatology arthritis cardiology joint agglutinin approach cold disease erythematosus extremity hematology hemolytic infectiousdiseases lupus management monoarthritis monoarticular oligoarthritis oligoarticular
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... Ewing sarcoma • Legg-Calve-Perthes ... Pain: • Infection ... #pain #differential ... #extremity #msk
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... night sweats, fever ... Marantic (NTBE) Differential ... Leukocytosis, anemia ... Persistent bacteremia/fevers
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Arthritis Differential ... • Rheumatic fever ... • Bacterial endocarditis ... #Differential # ... Diagnosis #MSK #
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential ... involves aortic and mitral ... night sweats, fever ... Leukocytosis, anemia ... #Endocarditis #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
infection, autoimmune ... negative anti-lgG ... younger pts) Differential ... Symptoms: High fevers ... chills, flank pain
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... acute rheumatic fever ... • Acute = Viral ... #Joint #Pain #MSK ... approach #workup #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
arthralgia, arm/leg ... tract: Abdominal pain ... the upper and lower ... legs), cutaneous ... infection, drug
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Arthritis: • Joint pain ... (hypertension, lower ... • Libman-Sacks endocarditis ... Cytopenias • Cardiac valve
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