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differential management pulmonary autoimmune common diseases hematology hypogammaglobulinemia immunodeficiency immunology induced interstitial myopathy myositis toxicity toxicology variable
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... : Amiodarone, Nitrofurantoin ... Churg Strauss syndrome ... #diagnosis #differential ... #pulmonary #causes
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Lung Toxicity Summary ... Direct cytotoxic lung ... respiratory distress syndrome ... Exclusion of other ILDs ... #Induced #Lung
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... community-acquired infections: Pneumonia ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... of aspiration pneumonia ... of aspiration pneumonia ... statins - probably caused
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