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amiodarone antinxp2dm autoimmune common cvid dermatology dermatomyositis differential hematology hypogammaglobulinemia immunodeficiency immunology induced myopathy myositis pulmonary sjogrens toxicity toxicology variable
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... community-acquired infections: Pneumonia ... DDX - Other causes ... : • Nephrotic syndrome ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... respiratory distress syndrome ... Exclusion of other ILDs ... #management #Toxicology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Muscle atrophy may cause ... Dermatomyositis: • ILD ... was diagnosed in ... #diagnosis #management ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Usual interstitial pneumonia ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... of aspiration pneumonia ... of aspiration pneumonia ... statins - probably caused
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