5 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... → Hypokalemia Metabolic ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Citrate Anticoagulation Toxicity

Hypernatremia (HyperNa):
 - Citrate solutions may have ↑ sodium content and should be paired
Toxicity Hypernatremia ... dysfunction or low ... metabolism Metabolic ... Toxicity #toxicology #nephrology ... #diagnosis
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
How do you work ... suspicion) • +/- bubble ... #stroke #workup ... #diagnosis #checklist ... #neurology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Normal/low ... Bartter syndrome, Gitelman ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... alkalosis • Normal or low ... Hypochloremic metabolic ... #Syndrome #diagnosis ... #nephrology #management