8 results
Classification of Neonatal Seizures
Subtle 
Clonic 
 - Focal 
 - Multifocal 
Tonic 
 - Focal
Neonatal Seizures Subtle ... Classification #Diagnosis ... #Peds #Pediatrics ... #Neurology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... in the distal tubule ... Hypokalemia Metabolic alkalosis ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... Diagnosis ECF ... indicates a renal tubule ... #Differential #Diagnosis ... #Causes #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... in the proximal tubule ... the indicated causes ... urine #Algorithm #nephrology ... #differential #diagnosis
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... the underlying cause ... until cause identified ... #management #neurology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... Hypochloremic metabolic alkalosis ... Gitelman #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
anemia (MAHA) Pathophysiology ... , add other BP meds ... • Refractory cases ... #rheumatology #nephrology ... #diagnosis #management