13 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
disomy: inheriting 2 ... Signs/Symptoms ... Obesity -> Type 2 ... #genetics #pathophysiology ... #peds #pediatrics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Onset Alzheimer's (1% ... - Presenilin 1 ... and 2 gene mutations ... - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... While the pathophysiology ... young (less than 2 ... Clinical #Video #PhysicalExam ... #Pediatrics #Peds
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... Specific sarcoidosis syndromes ... symptoms) • Löfgren syndrome ... • Heerfordt syndrome ... Diagnosis #Management #Signs
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
conditions exist: (1) ... hydrostatic pressure (2) ... type 1 (reflex ... Lower #Extremity #PhysicalExam ... #Pathophysiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
weakness in: 1. ... Ptosis, diplopia 2. ... EMG Findings: 1. ... - Peek sign ... 2.
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... PRES Diagnosis: 1. ... : Acute onset 2. ... 105 mmHg within 2 ... Seizures: Treat with AEDs
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
is also a late sign ... normally extends 1— ... 2 cm below the costal ... Newborn #Infant #PhysicalExam ... #Examination #Peds
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... safe to stop 2. ... • Examine for signs ... caseyalbin #PhysicalExam
Double Shunt on Echocardiogram
What do you see on this saline contrast study, in a patient with
1. ... Early transit of bubbles ... = PFO 2. ... syndrome #1: Pulm ... stretched PFO or ASD