13 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Onset Alzheimer's (1% ... - Presenilin 1 ... mutations - Down syndrome ... AlzheimersDisease #Dementia ... #pathophysiology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
and workup 1) ... Aphaso-apraxo-agnosia syndrome ... atrophy Lewy body dementia ... (parkinsonian signs ... Frontotemporal dementia
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... , Deafness Signs ... slowness, Psychosis/dementia ... Carpal timel syndrome ... Symptoms #Diagnosis #PhysicalExam
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... prevalence of 1- ... in the distal tubule ... #Pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... hemianopsia IGF-1 ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... endocrinology #pathophysiology
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
conditions exist: (1) ... type 1 (reflex ... • SVC syndrome ... Lower #Extremity #PhysicalExam ... #Pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... Specific sarcoidosis syndromes ... symptoms) • Löfgren syndrome ... • Heerfordt syndrome ... Diagnosis #Management #Signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... Comatose Patient 1. ... • Examine for signs ... caseyalbin #PhysicalExam
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
is also a late sign ... Down syndrome is ... are observed for signs ... normally extends 1— ... Newborn #Infant #PhysicalExam
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
approximately 1 ... seen in Reiter's syndrome ... Diagnosis #Clinical #Signs ... #PhysicalExam #