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nephrology diagnosis alkalosis differential metabolic algorithm causes chloride defects fanconi hypokalemia liddle localization nephron urinary urine
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Bartter Syndrome ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
indicates a renal tubule ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... other • Severe potassium ... Diagnosis #Causes #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia ... in the proximal tubule ... of sodium and potassium
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