29 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
: Proximal tubule ... Distal convoluted tubule ... : Collecting tubule ... Nephron #Defects #Pathophysiology ... #Nephrology
Parinaud's Syndrome
What?
 - Impaired upgaze
 - Light-near dissociation
 - Convergence retraction nystagmus
 - Eyelid retraction (Collier's
Parinaud's Syndrome ... retraction (Collier's sign ... tumors - Multiple Sclerosis ... → "setting sun sign ... diagnosis #pineal #neurology
Parinaud's syndrome
What?
 • Light-near dissociation (tectal pupils)
 • Convergence retraction nystagmus
 • Eyelid retraction (Collier's sign)
Parinaud's syndrome ... retraction (Collier's sign ... tumors • Multiple sclerosis ... "setting sun" sign ... #neurology #diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... • Lhermitte’s sign ... objective evidence of neurologic ... #diagnosis #management ... #neurology #treatment
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... in the distal tubule ... #Pathophysiology ... #nephrology #diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral Sclerosis ... finding of lateral sclerosis ... Pathophysiology ... #neurology #diagnosis ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... disease, Multiple sclerosis ... SPS #Diagnosis #Management ... #treatment #neurology
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
One and a Half Syndrome ... An APD was noted ... One and a Half Syndrome ... , and multiple sclerosis ... ophthalmology #neurology